Alternating versus hybrid MOPP-ABVD in Hodgkin's disease: The Milan experience
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چکیده
منابع مشابه
AUTOLOGOUS MARROW TRANSPLANTATION IN THE TREATMENT OF MOPP AND ABVD-RESI STANT HODGKIN\'S DISEASE
Six patients with disseminated Hodgkin's disease resistant to MOPP (mechlorethamine, vincristine, procarbazine and prednisolone), and ABVD (adriamycin, bleomycin, vinblastine and dacarbazine) chemotherapy were treated with high-dose chemotherapy and autologous marrow transplantation. The patients first underwent marrow aspiration and storage for subsequent autologous bone marrow transplant...
متن کاملAlternating MOPP and ABVD chemotherapy plus mantle-field radiation therapy in patients with massive mediastinal Hodgkin's disease.
PURPOSE To evaluate the efficacy and toxicity of mechlorethamine, vincristine, procarbazine, and prednisone (MOPP)/doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) chemotherapy plus mantle-field radiation therapy in the treatment of patients with massive mediastinal Hodgkin's disease of any stage. PATIENTS AND METHODS Eighty patients presented with Hodgkin's disease and a mediastin...
متن کاملRandomized comparison of ABVD and MOPP/ABV hybrid for the treatment of advanced Hodgkin's disease: report of an intergroup trial.
PURPOSE In a series of trials, doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) and mechlorethamine, vincristine, procarbazine, prednisone, doxorubicin, bleomycin, and vinblastine (MOPP/ABV) have been identified as effective treatments for Hodgkin's disease. We compared these regimens as initial chemotherapy for Hodgkin's disease. PATIENTS AND METHODS Adult patients (N = 856) with ...
متن کاملautologous marrow transplantation in the treatment of mopp and abvd-resi stant hodgkin's disease
six patients with disseminated hodgkin's disease resistant to mopp (mechlorethamine, vincristine, procarbazine and prednisolone), and abvd (adriamycin, bleomycin, vinblastine and dacarbazine) chemotherapy were treated with high-dose chemotherapy and autologous marrow transplantation. the patients first underwent marrow aspiration and storage for subsequent autologous bone marrow transplant...
متن کاملTreatment of Hodgkin's disease in children with alternating mechlorethamine, vincristine, procarbazine, and prednisone (MOPP) and adriamycin, bleomycin, vinblastine, and dacarbazine (ABVD) courses without radiotherapy.
Since the introduction of mechlorethamine, vincristine, procarbazine, and prednisone (MOPP) chemotherapy, children with Hodgkin's disease (HD) have been treated with chemotherapy alone. The occurrence of side effects related to irradiation (especially secondary solid tumors) is less likely to occur. Alkylating agents in the MOPP chemotherapy combinations are, however, known for their late effec...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 1991
ISSN: 0923-7534
DOI: 10.1093/annonc/2.suppl_2.55